Expression of RAR? and RAR? in human oral potentially malignant and neoplastic lesions

CD2 expression and the PML-RAR gene.

Expression of ABCG2 and Bmi-1 in oral potentially malignant lesions and oral squamous cell carcinoma

Early diagnosis is vital for effective treatment of oral squamous cell carcinoma (OSCC). The optimal time for clinical intervention is prior to malignancy when patients present with oral potentially malignant lesions such as leukoplakia or erythroplakia. Transformation rates for oral dysplasia vary greatly and more rigorous methods are needed to predict the malignant potential of oral lesions. ...

Nuclear receptors RXR :RAR are repressors for human MRP3 expression

Chen W, Cai SY, Xu S, Denson LA, Soroka CJ, Boyer JL. Nuclear receptors RXR :RAR are repressors for human MRP3 expression. Am J Physiol Gastrointest Liver Physiol 292: G1221–G1227, 2007. First published February 1, 2007; doi:10.1152/ajpgi.00191.2006.—Multidrug resistanceassociated protein MRP3/Mrp3 (ABCC3) is upregulated in cholestasis, an adaptive response that may protect the liver from accum...

Potentially malignant oral lesions: clinicopathological correlations

OBJECTIVE To determine the incidence of potentially malignant oral lesions, and evaluate and correlate their clinical and pathological aspects. METHODS The sample consisted of cases clinically diagnosed as oral leukoplakia, oral erythroplakia, erythroleukoplakia, actinic cheilitis, and oral lichen planus treated at a diagnostic center, between May 2012 and July 2013. Statistical tests were co...

Evaluation of AgNORs in Oral Potentially Malignant Lesions

Oral squamous cell carcinoma (OSCC) is usually preceded by detectable mucosal changes, as leukoplakias and erythroplakia. Histologically, these lesions can range from hyperkeratosis and acanthosis to epithelial dysplasia and even OSCC. The aim of this study was to investigate the proliferative activity, using AgNORs quantification proteins, in low- and high-risk oral epithelial dysplasia, OSCC,...